Indications and usage of Actovegin:
– Brain metabolic and vascular disorders (incl. ischaemic stroke, traumatic brain injury);
– Peripheral vascular disorders (arterial and venous) and their aftermaths (arterial angiopathy, trophic ulcers);
– Diabetic polyneuropathy;
– Wounds repair process (ulcers of different origin, burns, pressure injuries, disorders of wound repair process);
– Prevention and treatment of skin and mucous coat radio-lesions associated with ray treatment.
Dosage and administration:
For intra-arterial/intravenous introduction (including in form of infusions) and intramuscular introduction. Due to the fact, that the drug can promote anaphylactic reactions, a test before the infusions should be made.
– Metabolic and vascular disorders of brain: from 5 ml to 25 ml (200-1000 mg) per day intravenous for 2 weeks followed with Actovegin administration in form of tablets.
– Ischaemic stroke: 20-50 ml (800-2000 mg) in 200-300 ml 0.9% sodium chloride solution or 5% dextroglucose solution, intravenous, once a day for 1 week, then 10-20 ml (400-800 mg) intravenous by drop infusion for 2 weeks followed with Actovegin administration in form of tablets.
– Peripheral vascular disorders (arterial and venous) and their after-effect: 20-30 ml (800-1000 mg) in 200 ml 0.9% sodium chloride solution or 5% dextroglucose solution, intravenous or intra-arterial once a day; treatment duration should be no less than 4 weeks.
– Diabetic polyneuropathy: 50 ml (2000 mg) per day intravenous for 3 weeks followed with Actovegin administration in form of tablets – 2-3 tablets 3 times a day for 4-5 months.
– Wounds repair: 10 ml (400 mg) intravenous or 5 ml intramuscular once a day or 3-4 times a week (it depends on the healing process). The treatment should be complemented with topical form of Actovegin.
– Prevention and treatment of skin and mucous coat radio-lesions during radiation treatment: an average dose is 5 ml (200 mg) intravenous once a day during the intervals between radiation exposure.
– Radiation induced cystitis: 10 ml (400 mg) transurethically once a day along with antibiotics therapy. Rate of administration – 2 ml per minute. Treatment duration should be determined individually in accordance with symptoms and disease severity.